The signs and symptoms of Crohn’s disease can range from mild to severe and sporadic to chronic. When the disease is in remission (inactive), you may not have any symptoms. However, when the disease is active, you may experience diarrhea, abdominal pain, abdominal cramping, blood in the stool, reduced appetite, weight loss, malnutrition, and ulcers in the intestines and mouth. Other symptoms may include fatigue, fever, skin disorders, arthritis, bile ducts or liver inflammation, and eye inflammation.

It is not clear why these other problems occur. The immune system may trigger inflammation in other parts of the body when there is inflammation in the gut.

These other problems tend to go when the gut symptoms settle, but not always.

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